Human cytomegalovirus (HCMV) glycoprotein M occurs in three distinct genotypes in laboratory strains and clinical isolates
Glycoprotein M is highly conserved, but we have identified three distinct genotypes, arising from variability in a small region of the genome. These changes altered the predicted hydrophobicity of the glycoprotein potentially altering the conformational structure of the glycoprotein and affecting its function in vivo.
Authors
- Simon C. Lovell (ORCID: https://orcid.org/0000-0002-4092-8458)
- Pamela Vallely (ORCID: https://orcid.org/0000-0002-7712-9131)
- Zahrah Buhamad
- Paul E. Klapper (ORCID: https://orcid.org/0000-0002-9554-4857)
- Alia Al-Alfard
- Julia Duffey
Institutions
- University of Manchester (GB)
Publication Details
- Journal
- Journal of Clinical Virology
- Published
- 2025-04-20
- DOI
- https://doi.org/10.1016/j.jcv.2025.105799
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00