Prophylactic supplementation with biogenic selenium nanoparticles mitigated intestinal barrier oxidative damage through suppressing epithelial-immune crosstalk with gut-on-a-chip
These results indicated that biogenic SeNPs reinforced antioxidant enzyme defenses, maintained mitochondrial homeostasis, inhibited crosstalk between inflammatory cells and intestinal epithelial cells, thereby protecting the intestinal epithelial barrier against oxidative stress damage.
Authors
- Xiaofan Song
- Jiajing Chang
- Chunlan Xu (ORCID: https://orcid.org/0000-0002-0139-5046)
- Xiaonan Zeng
- Xina Dou
- Lei Qiao (ORCID: https://orcid.org/0000-0003-2907-7629)
- Li Ren
- Ge Yang (ORCID: https://orcid.org/0000-0002-2624-4412)
- Tianjing Deng
Institutions
- Northwestern Polytechnical University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-04-20
- DOI
- https://doi.org/10.1016/j.jare.2025.04.023
- Citations
- 8
- Primary Topic
- Selenium in Biological Systems
- Type
- article
- Field-Weighted Citation Impact
- 8.96