Guillain–barre syndrome (GBS) rise in complications due to diagnostic pitfalls: A case report

Guillain-Barre syndrome (GBS) is an abrupt, complex degenerative neurological condition that can manifest as either acute or chronic. It has been observed that antecedent infections serve as significant risk factors for acquiring GBS, in current case study we observed the antecedent infection of Chikungunya virus and recent history of Covid 19 vaccination. Although the aetiology is yet unknown, the pathophysiology demonstrates demyelination of the spinal nerve roots, which is marked by muscle stiffness and symmetrical limb paralysis.In cases of severity, early diagnosis and immediate treatment are crucial. Here we discuss the case of GBS with complications due to diagnostic pitfalls. This case study focuses on 60 years old male patient exhibiting the complaints of paraesthesia in lower limb and increasing muscle weakness.In this case firstlythe patient was misdiagnosed with appearance of small hypodensity in left caudate nucleus in CT scan study of brain. After one week patient’s conditions was getting worseand shifted to another hospital for further diagnosis and treatment. After thatin radiological examination of brain (CT scan) atrophic alterations were seen.Cerebrospinal fluid analysis and Nerve Conduction Velocity study showed demyelinating polyradiculoneuropathy like AIDP type of GBS.In this case study patient was treated with intravenous immunoglobulin (IVIG) transfusion for 5 days and progress of slight movements of limbs was observed.The significance of precise diagnosis and prompt implementation of suitable treatment approaches in the management of GBS is highlighted by this case study.