Oncologic outcomes of surgically treated colorectal cancer in octogenarians: a comparative study using inverse probability of treatment weighting (IPTW)
After IPTW adjustment, age was not an independent factor affecting oncologic outcomes. Instead, emergency surgery, severe complications, advanced stage, tumor differentiation, and perineural invasion were significant predictors of survival and recurrence. In the subgroup analysis, octogenarians with no or mild complications had significantly better 3-year OS than those with severe complications. These findings suggest that perioperative management and disease severity, rather than age alone, should guide treatment decisions.
Authors
- Jae Young Kwak (ORCID: https://orcid.org/0000-0001-8263-2260)
- Keong Won Yun (ORCID: https://orcid.org/0000-0003-3293-4564)
- Chung Hyeun Ma (ORCID: https://orcid.org/0000-0002-7005-1079)
- Jung Yun Park
- Seong-A Jeong (ORCID: https://orcid.org/0000-0003-3813-4488)
- Kwang Hyun Yoon (ORCID: https://orcid.org/0000-0002-4071-3211)
- Yun Tae Jung (ORCID: https://orcid.org/0000-0002-3583-7105)
- Chang Sik Yu (ORCID: https://orcid.org/0000-0001-9401-9981)
- Yong Jae Kwon (ORCID: https://orcid.org/0000-0001-9490-1229)
- Soo Young Oh (ORCID: https://orcid.org/0000-0001-7320-0853)
- Kwan Mo Yang
Institutions
- Ulsan College (KR)
- University of Ulsan (KR)
- The Catholic University of Korea Yeouido St. Mary's Hospital (KR)
- Gangneung Asan Hospital (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-04-20
- DOI
- https://doi.org/10.1186/s12876-025-03882-3
- Citations
- 3
- Primary Topic
- Colorectal Cancer Screening and Detection
- Type
- article
- Field-Weighted Citation Impact
- 3.14