Maternal and cord serum levels of sFlt-1 and PlGF in pregnancies complicated by gestational diabetes mellitus: a prospective cohort study
Results revealed that maternal sFlt-1, PlGF, and sFlt-1/PlGF ratios are not vital biomarkers of endothelial dysfunction and angiogenic imbalance in GDM, but low cord serum PlGF and sFlt-1 levels may reflect the chronic fetal hypoxia and increased placental angiogenesis in diabetic pregnancies.
Authors
- Nasuh Utku Doğan (ORCID: https://orcid.org/0000-0002-3380-7607)
- Sebahat Özdem (ORCID: https://orcid.org/0000-0002-0619-1405)
- Saniye Merve Gül Kara (ORCID: https://orcid.org/0000-0002-9449-7913)
- İkbal Özen Küçükçetin (ORCID: https://orcid.org/0000-0002-4541-013X)
- Gül Alkan Bülbül (ORCID: https://orcid.org/0000-0002-6773-4573)
- Hülya Kandemir (ORCID: https://orcid.org/0000-0001-8218-1893)
- Cem Yaşar Sanhal (ORCID: https://orcid.org/0000-0003-0007-5769)
- Emine Kirtiş (ORCID: https://orcid.org/0000-0002-6017-8228)
Institutions
- Akdeniz University (TR)
Publication Details
- Journal
- The Journal of Maternal-Fetal & Neonatal Medicine
- Published
- 2025-04-20
- DOI
- https://doi.org/10.1080/14767058.2025.2491454
- Citations
- 4
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 8.23