A New Antifungal 3,4‐Dimethoxybenzoate Dimer Artefact Formed During Isolation of <i>Aconitum georgei</i> Comber Constituents
A new 3,4-dimethoxybenzoate dimer, georgedimer (1), was obtained from the roots of Aconitum georgei Comber, along with 12 known compounds (2-13) isolated from this species. Their structures were established on the basis of extensive spectroscopic analyses. The results of the antifungal activities indicated that compounds 1, 5, 6, 7, and 8 exhibited antifungal activity against several plant pathogens, including Fusarium solani, F. oxysporum, Plectosphaerella cucumerina, and Alternaria panax, with minimum inhibitory concentration values ranging from 8 to 64 µg/mL.
Authors
- Jia-Peng Wang (ORCID: https://orcid.org/0000-0002-1702-7029)
- Le Cai (ORCID: https://orcid.org/0000-0003-0970-4920)
- Yuxi Duan (ORCID: https://orcid.org/0000-0002-6287-6812)
- Zhiming Zhang (ORCID: https://orcid.org/0000-0003-3116-756X)
- Jiaxin Liu (ORCID: https://orcid.org/0009-0004-2527-6502)
- Yan Shu (ORCID: https://orcid.org/0000-0002-0035-5368)
- Wei Zhao (ORCID: https://orcid.org/0009-0004-1001-7866)
Institutions
- Yunnan University (CN)
- Yunnan Provincial Department of Education (CN)
- Dali University (CN)
Publication Details
- Journal
- Chemistry & Biodiversity
- Published
- 2025-04-20
- DOI
- https://doi.org/10.1002/cbdv.202403298
- Primary Topic
- Plant-based Medicinal Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Yunnan University
- National Ethnic Affairs Commission of the People's Republic of China