Homocysteine Mediates Cognitive Inflexibility Induced by Stress via Targeting PIN1
These results suggest that the impairment of cognitive flexibility induced by stress can be inhibited by regulating the content of HCY. Collectively, our findings highlight therapeutic strategies aimed at improving HCY treatment for impairments in cognitive flexibility.
Authors
- Ling Zhang (ORCID: https://orcid.org/0000-0002-1532-680X)
- Shijia Zhang
- Yun Fu Zhao (ORCID: https://orcid.org/0000-0002-6357-9422)
- Xiaobing Chen (ORCID: https://orcid.org/0000-0002-6831-1417)
- Bing Liu (ORCID: https://orcid.org/0000-0002-7313-6924)
- Xue Chao Wang (ORCID: https://orcid.org/0000-0002-2381-9145)
- Huafeng Dong
- Fang Xie (ORCID: https://orcid.org/0000-0002-6573-035X)
- Zhaowei Sun (ORCID: https://orcid.org/0000-0002-3195-0186)
- Lingjia Qian
Institutions
- Beijing Institute of Education (CN)
- Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences
Publication Details
- Journal
- Brain Sciences
- Published
- 2025-04-19
- DOI
- https://doi.org/10.3390/brainsci15040416
- Primary Topic
- Signaling Pathways in Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00