Cuproptosis-induced up-regulation of RBM24 suppresses tumor metastasis via MAPK signaling blockage in colorectal cancer
Elevated levels of cuproptosis-induced cell death disrupt the MAPK signaling cascade, thus suppressing the metastasis of CRC. This discovery sheds new light on the potential application of cuproptosis in oncological treatments.
Authors
- Xiaodong Han (ORCID: https://orcid.org/0000-0003-4512-3699)
- Tianchen Huang
- Dongxiao Bai (ORCID: https://orcid.org/0000-0001-5030-2814)
- Lei Li (ORCID: https://orcid.org/0009-0004-7611-4829)
- Kan Li (ORCID: https://orcid.org/0000-0002-5762-7440)
- Yong Zhang (ORCID: https://orcid.org/0000-0002-1303-0458)
- Yachao Wu
- Zhi‐Peng Guo (ORCID: https://orcid.org/0000-0001-8193-6086)
- Weijie Wang
- Yanshan Xin
Institutions
- Anyang Tumor Hospital (CN)
Publication Details
- Journal
- Archives of Medical Science
- Published
- 2025-04-20
- DOI
- https://doi.org/10.5114/aoms/199363
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00