Contribution of dopaminergic polymorphisms to levodopa treatment response and drug concentration in Chinese patients with Parkinson’s disease
Our preliminary results from a relatively small patients' sample, may suggest that the rs6356 polymorphism in the TH gene could act as a possible modifier of levodopa response in PD.
Authors
- Qin Xiao
- Xiaoqin He (ORCID: https://orcid.org/0000-0003-0319-9345)
- Chengjun Mo (ORCID: https://orcid.org/0000-0003-1644-6413)
- Kai Shi (ORCID: https://orcid.org/0000-0001-5351-1910)
- Yi Zhang (ORCID: https://orcid.org/0000-0002-6837-4258)
- Xiaodong Yang (ORCID: https://orcid.org/0000-0002-4701-1204)
Institutions
- Qingdao University (CN)
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
- Qingdao Municipal Hospital (CN)
Publication Details
- Journal
- Clinical Parkinsonism & Related Disorders
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.prdoa.2025.100333
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China
- Shanghai Rising-Star Program
- National Key Research and Development Program of China