APOE suppresses osteosarcoma by modulating ferroptosis through the mTOR/Stat3 signaling pathway
<i>APOE</i> overexpression suppresses osteosarcoma growth by promoting ferroptosis and autophagy through the mTOR/Stat3 signaling pathway, highlighting its promise as a target for OS therapeutic intervention.
Authors
- Xiangyang Cheng (ORCID: https://orcid.org/0009-0004-2488-803X)
- Chong Bian (ORCID: https://orcid.org/0009-0005-1802-9033)
- Guangnan Chen (ORCID: https://orcid.org/0000-0003-0648-7780)
- Huijie Gu (ORCID: https://orcid.org/0000-0002-6044-4979)
- Yiming Zhang (ORCID: https://orcid.org/0009-0009-2403-0072)
- Liang Wu (ORCID: https://orcid.org/0000-0001-8533-5042)
Institutions
- Fudan University (CN)
- Minhang District Central Hospital (CN)
Publication Details
- Journal
- Archives of Medical Science
- Published
- 2025-04-20
- DOI
- https://doi.org/10.5114/aoms/203990
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00