IGF-1 promotes trophectoderm cell proliferation of porcine embryos by activating the Wnt/β-catenin pathway
Our findings provide new insights into the interaction between IGF-1 and the Wnt/β-catenin signaling pathway during embryogenesis and highlight the potential of IGF-1 to improve reproductive outcomes by enhancing TE formation and quality.
Authors
- Sun‐Uk Kim (ORCID: https://orcid.org/0000-0002-5168-6976)
- Bo‐Woong Sim (ORCID: https://orcid.org/0000-0002-4492-1085)
- Se‐Been Jeon (ORCID: https://orcid.org/0009-0005-1944-8299)
- Seong‐Keun Cho (ORCID: https://orcid.org/0000-0001-9309-2327)
- Bong‐Seok Song (ORCID: https://orcid.org/0000-0002-0489-6719)
- Pil‐Soo Jeong (ORCID: https://orcid.org/0000-0002-8477-4358)
- Ji Hyeon Yun
- Eun Young Choi (ORCID: https://orcid.org/0000-0002-1668-6452)
- Min Ju Kim (ORCID: https://orcid.org/0009-0009-5126-4317)
- Hyo‐Gu Kang
Institutions
- Hankyong National University (KR)
- Chungnam National University (KR)
- Pusan National University (KR)
- Korea Research Institute of Bioscience and Biotechnology (KR)
- Korea University of Science and Technology (KR)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-04-20
- DOI
- https://doi.org/10.1186/s12964-025-02191-2
- Citations
- 4
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 7.51
Funders
- Korea Research Institute of Bioscience and Biotechnology