Effects of 3D-printed exosome-functionalized brain acellular matrix hydrogel on neuroinflammation in rats following cerebral hemorrhage
The findings demonstrate that the 3D biological scaffold dECM@exo effectively maintains microenvironmental homeostasis in the early stages of ICH and improves outcomes associated with the condition. dECM@exo is poised to serve as a robust platform for drug delivery and biotherapy in ICH treatment, offering a viable alternative for managing this condition.
Authors
- Chengrui Nan
- Aobo Zhang (ORCID: https://orcid.org/0000-0003-0568-8601)
- Boyu Sun
- Lin William Cong (ORCID: https://orcid.org/0000-0002-2617-2367)
- Zongmao Zhao (ORCID: https://orcid.org/0000-0002-3753-3949)
- Liqiang Liu (ORCID: https://orcid.org/0000-0001-5325-9399)
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-04-20
- DOI
- https://doi.org/10.1186/s13287-025-04332-3
- Citations
- 5
- Primary Topic
- Tissue Engineering and Regenerative Medicine
- Type
- article
- Field-Weighted Citation Impact
- 10.03
Funders
- Health Commission of Hebei Province