Alleviating penicillin-resistant Streptococcus pneumoniae‑induced lung epithelial cell injury: mechanistic insights into effects of the optimized combination of main components from Yinhuapinggan granules
Taken together, our results suggest that CAP can modulate or synergize with PG to modulate the TLRs/MyD88 pathway and attenuate PRSP-induced lung injury, and can be used as a potential drug for treating PRSP infection.
Authors
- Haitong Wan (ORCID: https://orcid.org/0000-0001-5726-7214)
- Jialiang Lv (ORCID: https://orcid.org/0000-0001-6771-6570)
- Haofang Wan (ORCID: https://orcid.org/0000-0001-5055-312X)
- Daojun Yu (ORCID: https://orcid.org/0000-0003-0855-7420)
- Wenba Wang
- Huifen Zhou
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-04-20
- DOI
- https://doi.org/10.1186/s12879-025-10951-1
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China