In Vitro and In Vivo Assessment of an Innovative Peeling System with Azelaic and Tranexamic Acids for Targeted Hyperpigmentation Reduction
These data provide evidence for the efficacy of the innovative peeling system in reducing the appearance of hyperpigmentation over a 6-week treatment regimen in females with healthy skin and moderate-to-severe hyperpigmentation. The inclusion of AZA and TXA within the peeling system, along with active brightening and penetration-enhancing ingredients, may have synergistically facilitated the observed improvements. This multifaceted approach may address hyperpigmentation at the source, contributing to overall improvements in the appearance of the skin.
Authors
- Alexis R. Kim (ORCID: https://orcid.org/0000-0002-9830-7312)
- Kevin D. Hermanson
- Russell Wong (ORCID: https://orcid.org/0000-0003-3683-8983)
- James D. Sun
- Robert J. Bianchini
- Mariangela G. de O. Sichmann
- Louis Chabert
Institutions
- Unilever (United Kingdom) (GB)
- Covenant Health (CA)
- SomaLogic (United States) (US)
- Unilever (United States) (US)
Publication Details
- Journal
- Dermatology and Therapy
- Published
- 2025-04-20
- DOI
- https://doi.org/10.1007/s13555-025-01399-x
- Citations
- 3
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 3.45