A novel chemiresistive biosensor utilizing green-synthesized AgNPs and MWCNT-ZnO nanofibers for rapid detection of tuberculosis Lipoarabinomannan (LAM) antigen

This study concludes that the developed paper-based IDE sensor offers a highly sensitive, selective, and cost-effective solution for the early detection of TB antigens, with an impressive LOD of 25.79 fg/mL and a broad detection range. Its simple fabrication, disposable design, and environmentally friendly paper substrate make it ideal for point-of-care applications in resource-limited settings. This innovation is significant as it addresses critical diagnostic gaps, enabling early diagnosis and improved TB management, particularly in underserved regions where traditional methods fall short.