A STUDY OF ETIOLOGY, CLINICAL PROFILE AND PROGRESS IN PATIENTS WITH ACUTE KIDNEY INJURY IN A TERTIARY CARE HOSPITAL, BARABANKI

Background: Acute Kidney Injury (AKI) is a critical condition with diverse etiologies and variable prognoses. This study aims to identify the etiology, clinical profile, and progression of AKI in patients admitted to a tertiary care hospital. Objectives: To identify the varied etiology of AKI. To study the prognosis of AKI. To determine the outcomes of AKI correlated with AKIN Stage. Methods:Aprospective hospital-based study was conducted over 18 months at Dr. KNS Memorial Institute of Medical Science, Barabanki. Forty adult patients (24 males, 16 females) fulfilling AKIN criteria were enrolled. Demographic, biochemical, and clinical profiles were recorded, with serum creatinine measured at admission and follow-ups. Data analysis was performed using SPSS 23.0, applying Chi-square, t-test, and ANOVA, with statistical significance set at P <0.05. Results: The study assessed age, sex, type of AKI (pre-renal, renal, post-renal), risk factors, dialysis indications, and outcomes. Correlations between AKIN stages and prognosis were evaluated, showing a significant association with recovery or mortality rates. Conclusion: AKI has a multifactorial etiology, with outcomes influenced by AKIN stage and timely intervention. Identifying high-risk patients can aid in early diagnosis and management, improving survival rates. Further large-scale studies are recommended for better understanding and prevention strategies.