Association Between Rate of Hypernatremia Correction and Mortality: A Retrospective Cohort Study Across a Regional Health System

These findings add to the growing evidence challenging traditional concerns about rapid correction of hypernatremia in adults, suggesting that rapid correction rates exceeding 8 mmol/L/day do not increase mortality or cause adverse neurological events. These results support reconsidering rigid correction limits and highlight the need for further research on individualized treatment strategies.

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Publication Details

Journal
Cureus
Published
2025-04-19
DOI
https://doi.org/10.7759/cureus.82558
Citations
1
Primary Topic
Electrolyte and hormonal disorders
Type
article
Field-Weighted Citation Impact
1.52
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article

Association Between Rate of Hypernatremia Correction and Mortality: A Retrospective Cohort Study Across a Regional Health System

Mohammad Jawish, Keerthi Renjith, Omer Ahmed, Sanjana Ramakrishnan et al.
1 citations
Cureus
Electrolyte and hormonal disorders
1.52
article

Association Between Rate of Hypernatremia Correction and Mortality: A Retrospective Cohort Study Across a Regional Health System

Mohammad Jawish, Keerthi Renjith, Omer Ahmed, Sanjana Ramakrishnan, Hyun Sook Lee, Afrah Misbah
article en
1 citations

Abstract

These findings add to the growing evidence challenging traditional concerns about rapid correction of hypernatremia in adults, suggesting that rapid correction rates exceeding 8 mmol/L/day do not increase mortality or cause adverse neurological events. These results support reconsidering rigid correction limits and highlight the need for further research on individualized treatment strategies.

CureusVol. 17(4)
Unity Health System (US)
Good health and well-being
Openalex Percentile: Top 20%
Electrolyte and hormonal disorders
1.52
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