Acute Kidney Injury In Dengue Fever, One Year Hospital Based Cross Sectional Study

Arboviruses pose a significant public health challenge, particularly in tropical and subtropical regions, where they contribute to frequent epidemics with substantial economic and social impacts. Among them, the dengue virus (DENV), transmitted by Aedes mosquitoes, is the most prevalent arthropod-borne viral infection in humans. Dengue fever (DF) has a vast global footprint, with an estimated 2.5 billion people at risk, and outbreaks reported in over 100 countries, primarily in Southeast Asia, the Pacific, and the Americas. While traditionally considered an urban disease, dengue is increasingly affecting rural populations, particularly in Africa and the eastern Mediterranean. Dengue infection presents with a wide spectrum of clinical manifestations, ranging from mild febrile illness to severe dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS), which contribute to significant morbidity and mortality. The disease burden has escalated over the years due to increasing globalization, trade, and travel, leading to the introduction of virulent strains into new regions. Despite preventive measures, dengue remains endemic in many countries, including India, where seasonal outbreaks occur annually, particularly during the monsoon season.