CLINICO DEMOGRAPHIC AND RADIOLOGICAL PROFILE OF SYMPTOMATIC INTRACRANIAL ATHEROSCLEROTIC DISEASE PATIENTS

With a 15% chance of recurrence, intracranial atherosclerotic disease is one of the main causes of stroke. Finding the profile of risk factors and arteries that are more frequently affected in ICAD patients is vital. Thus, the goal of the study was to examine the clinical, radiological, and demographic profiles of patients who had symptomatic intracranial atherosclerotic disease. Retrospective analysis of patients with ages ranging from 18 to 100 years old who were admitted to a tertiary care hospital in India between January 2019 and December 2023 was conducted. Patients with angiographically proven intracranial atherosclerotic disease and symptoms suggestive of cerebral ischemia were included in this investigation. Among 200, 131 patients based on inclusion criteria were enrolled in the study and variables including demographics, risk factors, the vessel implicated, and degree of stenosis were evaluated. 131 of the 200 patients that were examined were part of the ICAD group, and their mean age was 62.60±10.94 years. In both groups, males were more frequently impacted. Smoking, drinking, CAD, diabetes mellitus, hypertension, and dyslipidemia were more common in the ICAD group (no statistical significance).The supraclinoid region of the ICA was the most frequently afflicted artery (left, 38.46 > Right, 23.07%), ; anterior circulation >posterior circulation (87.79 vs. 39.69).53.3% of supraclinoid ICA patients had moderate stenosis. In order to enhance preventative measures and identify new treatment targets, our study established the relationship between modifiable and non-modifiable risk factors and ICAD as well as the artery segment involved.