Characteristics of molecular epidemiology and transmitted drug resistance among newly diagnosed HIV-1 infections in Lishui, China from 2020 to 2023
This study revealed that the prevalence of TDR was at an intermediate level of drug resistance, and high levels of resistance were predominantly concentrated in efavirenz (EFV) and nevirapine (NVP) among the NNRTIs. Middle-aged and older infections represented a significant proportion of the molecular transmission network. This suggests that HIV surveillance and targeted prevention and treatment interventions are essential to reduce the risk of HIV transmission.
Authors
- Jiaji Ye
- Deyong Zhang (ORCID: https://orcid.org/0000-0002-3417-7926)
- Xiaolei Chen (ORCID: https://orcid.org/0000-0002-7511-7620)
- Jianhua Mei
- Dongqing Cheng
- Jinkai Li (ORCID: https://orcid.org/0000-0002-2257-211X)
- Jianliang Zhu
- Xiuying Chen (ORCID: https://orcid.org/0000-0003-2098-2817)
- Jie Yu (ORCID: https://orcid.org/0009-0006-8471-2815)
Institutions
- Zhejiang Chinese Medical University (CN)
- Lishui University (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-04-19
- DOI
- https://doi.org/10.1186/s12985-025-02734-6
- Citations
- 1
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 1.40