Effect of DNA methylation on inhibitor development in people with hemophilia A treated with FVIII concentrates
DMCs were identified in PBMC samples from HA patients with inhibitors. However, our data could not confirm the role of these CpG sites in affecting immune-regulatory pathways.
Authors
- Himani Chand (ORCID: https://orcid.org/0000-0001-9963-3075)
- Shermarke Hassan (ORCID: https://orcid.org/0000-0002-5045-636X)
- Roberta Palla (ORCID: https://orcid.org/0000-0001-8837-2367)
- Flora Peyvandi (ORCID: https://orcid.org/0000-0001-7423-9864)
- Andrea Cairo
Institutions
- University of Milan (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1016/j.rpth.2025.102858
- Citations
- 1
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- Ministero della Salute
- H2020 Marie Skłodowska-Curie Actions