Obinutuzumab-Induced Inflammatory Bowel Disease-Like Colitis

This case demonstrates a severe instance of obinutuzumab-induced pancolitis with IBD-like features, emphasizing the need for clinicians to consider drug-induced etiologies in patients presenting with new gastrointestinal symptoms during obinutuzumab therapy. Timely diagnosis and a multidisciplinary approach are crucial for effective management. Further reports are needed to better understand the full spectrum of gastrointestinal toxicity associated with obinutuzumab and guide future treatment.

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Publication Details

Journal
Case Reports in Oncology
Published
2025-04-18
DOI
https://doi.org/10.1159/000545677
Citations
1
Primary Topic
Microscopic Colitis
Type
article
Field-Weighted Citation Impact
1.35
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article

Obinutuzumab-Induced Inflammatory Bowel Disease-Like Colitis

Safwat Odeh, Ilana Levy Yurkovski, N. S. Nazarov, Amjad Mousa et al.
1 citations
Case Reports in Oncology
Microscopic Colitis
1.35
article

Obinutuzumab-Induced Inflammatory Bowel Disease-Like Colitis

Safwat Odeh, Ilana Levy Yurkovski, N. S. Nazarov, Amjad Mousa, Nadav Weijel, Olga Zelman
article en
1 citations

Abstract

This case demonstrates a severe instance of obinutuzumab-induced pancolitis with IBD-like features, emphasizing the need for clinicians to consider drug-induced etiologies in patients presenting with new gastrointestinal symptoms during obinutuzumab therapy. Timely diagnosis and a multidisciplinary approach are crucial for effective management. Further reports are needed to better understand the full spectrum of gastrointestinal toxicity associated with obinutuzumab and guide future treatment.

Case Reports in OncologyVol. 18(1)
Technion – Israel Institute of Technology (IL), Bnai Zion Medical Center (IL)
Good health and well-being
Openalex Percentile: Top 21%
Microscopic Colitis
1.35
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