Histopathological biomarkers in squamous cell carcinoma of the vulva: the prognostic relevance of tumor-infiltrating lymphocytes (TILs)—a retrospective study of 157 cases
The fast and cost-effective determination of the histological biomarkers iTILs and sTILs yields prognostic relevance in vulvar cancer. A potential integration within the routine diagnostic workflow could be globally feasible, even in resource-poor settings.
Authors
- Bashar Haj Hamoud (ORCID: https://orcid.org/0000-0002-1386-409X)
- Annette Hasenburg (ORCID: https://orcid.org/0000-0002-1547-4968)
- Laura Schnöder
- Gilbert Georg Klamminger (ORCID: https://orcid.org/0000-0001-5358-2751)
- Bernd Holleczek
- Marcus Schmidt (ORCID: https://orcid.org/0000-0003-1365-2414)
- Meletios P. Nigdelis (ORCID: https://orcid.org/0000-0003-3865-6833)
- Yaman Degirmenci (ORCID: https://orcid.org/0000-0002-3713-9490)
- Mathias Wagner
- Erich Solomayer
Institutions
- Johannes Gutenberg University Mainz (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Krebsregister Saarland (DE)
- Saarland University (DE)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-04-19
- DOI
- https://doi.org/10.1007/s12672-025-02381-x
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- European Society for Medical Oncology
- Universitätsmedizin der Johannes Gutenberg-Universität Mainz