LPCAT3 regulates the immune infiltration and prognosis of ccRCC patients by mediating ferroptosis and endoplasmic reticulum stress
LPCAT3was identified as a ccRCC biomarker and may regulate immune infiltration and prognosis in ccRCC by mediating ferroptosis and ERS. Thus, it has potential for exploitation as a prognostic and immune therapeutic target for patients with ccRCC.
Authors
- Rui Cui (ORCID: https://orcid.org/0000-0003-4464-0192)
- Haiying Guo (ORCID: https://orcid.org/0000-0002-6853-6149)
- Ning Yu (ORCID: https://orcid.org/0000-0002-7129-8727)
- Yuying Zhao (ORCID: https://orcid.org/0000-0002-0695-3238)
- Bei Feng (ORCID: https://orcid.org/0000-0002-8476-8628)
- Xiang Wang (ORCID: https://orcid.org/0000-0001-5433-9905)
Institutions
- Harbin Medical University (CN)
- Yangtze University (CN)
- Dalian Jinzhou First People's Hospital (CN)
- Affiliated Hospital of Taishan Medical University (CN)
- Fourth Affiliated Hospital of Harbin Medical University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-04-19
- DOI
- https://doi.org/10.1007/s12672-025-02283-y
- Citations
- 5
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 7.59
Funders
- Harbin Medical University