Rupture of the Ulnar Artery in a Case of Neurofibromatosis Type 1

Neurofibromatosis type 1 (NF1) is a genetic disorder involving an abnormality on chromosome 17, resulting in the production of the protein neurofibromin. Neurofibromin inhibits cell proliferation, and abnormalities in its encoding gene are hypothesized to trigger signals for proliferation, resulting in various lesions. Vascular fragility is a rare complication of NF1; however, ruptures of various vessels have also been reported. Here, we present a case of ulnar artery rupture treated endovascularly by puncturing the ipsilateral brachial artery, achieving excellent results.

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Journal
Cureus
Published
2025-04-19
DOI
https://doi.org/10.7759/cureus.82596
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
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article

Rupture of the Ulnar Artery in a Case of Neurofibromatosis Type 1

Toshitaka Ito, Takaaki Nakano
Cureus
Neurofibromatosis and Schwannoma Cases
article

Rupture of the Ulnar Artery in a Case of Neurofibromatosis Type 1

Toshitaka Ito, Takaaki Nakano
article en

Abstract

Neurofibromatosis type 1 (NF1) is a genetic disorder involving an abnormality on chromosome 17, resulting in the production of the protein neurofibromin. Neurofibromin inhibits cell proliferation, and abnormalities in its encoding gene are hypothesized to trigger signals for proliferation, resulting in various lesions. Vascular fragility is a rare complication of NF1; however, ruptures of various vessels have also been reported. Here, we present a case of ulnar artery rupture treated endovascularly by puncturing the ipsilateral brachial artery, achieving excellent results.

CureusVol. 17(4)
Shioda General Hospital (JP)
Good health and well-being
Openalex Percentile: Top 86%
Neurofibromatosis and Schwannoma Cases
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Rupture of the Ulnar Artery in a Case of Neurofibromatosis Type 1 — Toshitaka Ito, Takaaki Nakano · Cureus (2025) | TGRS Research Map | TGRS