There Was Something in the Air: A Case of Interstitial Lung Disease Associated With Continuous Positive Airway Pressure (CPAP) Foam Degradation and Inhalation Syndrome

Polyurethane foam degradation in ventilatory support devices led to a recall by Philips Respironics after users developed respiratory symptoms and noted a sediment in the tubing system of such devices. Foam degradation releases end products that have an irritative effect on the airway. Although the incidence of neoplastic processes did not increase among users, studies for other conditions are scant. The following case presents the association between the use of one of these devices and a new diagnosis of interstitial lung disease, which resolved upon discontinuation of the device, in a patient with obstructive sleep apnea and chronic obstructive pulmonary disease.

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Journal
Cureus
Published
2025-04-19
DOI
https://doi.org/10.7759/cureus.82595
Primary Topic
Obstructive Sleep Apnea Research
Type
article
Field-Weighted Citation Impact
0.00
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article

There Was Something in the Air: A Case of Interstitial Lung Disease Associated With Continuous Positive Airway Pressure (CPAP) Foam Degradation and Inhalation Syndrome

Gangacharan Dubey, Ma D Valdes Bracamontes
1 links
Cureus
Obstructive Sleep Apnea Research
article

There Was Something in the Air: A Case of Interstitial Lung Disease Associated With Continuous Positive Airway Pressure (CPAP) Foam Degradation and Inhalation Syndrome

Gangacharan Dubey, Ma D Valdes Bracamontes
article en

Abstract

Polyurethane foam degradation in ventilatory support devices led to a recall by Philips Respironics after users developed respiratory symptoms and noted a sediment in the tubing system of such devices. Foam degradation releases end products that have an irritative effect on the airway. Although the incidence of neoplastic processes did not increase among users, studies for other conditions are scant. The following case presents the association between the use of one of these devices and a new diagnosis of interstitial lung disease, which resolved upon discontinuation of the device, in a patient with obstructive sleep apnea and chronic obstructive pulmonary disease.

CureusVol. 17(4)
SUNY Downstate Health Sciences University (US), VA NY Harbor Healthcare System (US)
Good health and well-being
Openalex Percentile: Top 90%
Obstructive Sleep Apnea Research
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There Was Something in the Air: A Case of Interstitial Lung Disease Associated With Continuous Positive Airway Pressure (CPAP) Foam Degradation and Inhalation Syndrome — Gangacharan Dubey, Ma D Valdes Bracamontes · Cureus (2025) | TGRS Research Map | TGRS