Proteogenomic verifies targets underlying erythromycin alleviate neutrophil extracellular traps-induced inflammation
Our study provides a comprehensive proteogenomic characterization of how EM alleviates NET-related inflammation, and identify PI3K/AKT play a critical role in the mechanism by which EM inhibits inflammation.
Authors
- fangling chen
- Xiao Yi (ORCID: https://orcid.org/0000-0002-6288-5233)
- Nan Ma (ORCID: https://orcid.org/0000-0002-8518-5627)
- Q Chen (ORCID: https://orcid.org/0009-0005-6237-3771)
- Meng Li (ORCID: https://orcid.org/0000-0001-5848-3832)
- Zhiyi He (ORCID: https://orcid.org/0000-0002-6146-7865)
- Xiao Liang (ORCID: https://orcid.org/0000-0001-8318-9459)
- Li Guo
- G.X. Pei
Institutions
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- Respiratory Research
- Published
- 2025-04-19
- DOI
- https://doi.org/10.1186/s12931-025-03226-5
- Citations
- 3
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 2.39
Funders
- National Natural Science Foundation of China