Unraveling the mechanisms of Shaoyang Shenggu decoction in treating knee osteoarthritis through mass spectrometry and bioinformatics
SYSGF may inhibit chondrocyte phenotype transformation and inflammation to improve KOA by regulating these key proteins, and is associated with the MAPK signaling pathway, HIF-1 signaling pathway, and PI3K-Akt signaling pathway.
Authors
- Yunlong Xiao (ORCID: https://orcid.org/0000-0003-0770-1240)
- G Wang (ORCID: https://orcid.org/0009-0007-7568-6915)
- Huarui Shen (ORCID: https://orcid.org/0009-0004-8038-4215)
- Zhang LongLong
- Fei Liu (ORCID: https://orcid.org/0000-0003-0064-7827)
- Zhuang Ding (ORCID: https://orcid.org/0000-0002-4833-6553)
- Wenhao Yang (ORCID: https://orcid.org/0000-0001-6228-8917)
- Jingchi Li (ORCID: https://orcid.org/0009-0001-3411-4810)
Institutions
- Southwest Medical University (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2025-04-19
- DOI
- https://doi.org/10.1016/j.jep.2025.119835
- Citations
- 3
- Primary Topic
- Traditional Chinese Medicine Studies
- Type
- article
- Field-Weighted Citation Impact
- 7.14