STUDY OF THE THERAPEUTIC EFFECTS OF PLACENTA AND SPLEEN CRYOEXTRACTS IN AN AUTOIMMUNE THYROIDITIS MODEL: CHANGES IN HORMONAL BALANCE

Background. Autoimmune thyroiditis (AIT) is a chronic inflammatory disorder of the thyroid gland driven by an autoimmune response, leading to impaired thyroid function. This condition typically results in lowered levels of key thyroid hormones, including triiodothyronine (T3) and thyroxine (T4), contributing to a range of symptoms such as fatigue, depression, metabolic imbalances, and disruptions in body temperature regulation. Given the complex nature of thyroid dysfunction, which involves multiple pathophysiological mechanisms, there is an ongoing need to explore novel therapeutic strategies aimed at restoring normal hormonal balance [1, 2]. One such promising approach is the use of cryoextracts, particularly those derived from the placenta (CEP) and spleen (CES), which are believed to have regenerative effects and may offer potential in correcting thyroid dysfunction in autoimmune conditions like AIT.