Impact of Islet Transplantation on Diabetes Complications and Mortality in Patients Living With Type 1 Diabetes

This study suggests long-term benefits of IT on diabetes-related outcomes. Furthermore, despite the use of immunosuppressive drugs following IT, we observed no significant increase in the risk of cancer. Altogether, these findings highlight a favorable risk-benefit ratio of IT in treating patients with unstable T1D.

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Publication Details

Journal
Diabetes Care
Published
2025-04-17
DOI
https://doi.org/10.2337/dc25-0059
Citations
6
Primary Topic
Pancreatic function and diabetes
Type
article
Field-Weighted Citation Impact
12.04

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article

Impact of Islet Transplantation on Diabetes Complications and Mortality in Patients Living With Type 1 Diabetes

Emmanuel Morélon, Sandrine Lablanche, Camille Besch, Orianne Villard et al.
6 citations
Diabetes Care
Pancreatic function and diabetes
12.04
article

Impact of Islet Transplantation on Diabetes Complications and Mortality in Patients Living With Type 1 Diabetes

Emmanuel Morélon, Sandrine Lablanche, Camille Besch, Orianne Villard, Sophie Borot, Thomas Jouvé, V. Melki, Matthieu Roustit, M. Heim, Clément Jambon-Barbara, François Faitot, Bénédicte Janbon, Andrea Peloso, Sabrina Granziera, Géraldine Parnaud, Fanny Buron, M.N. Peraldi, Antoine Dürrbach, Fanny Lebreton, Marie‐Christine Vantyghem, Éric Renard, Luc Rakotoarisoa, Nadine Pernin, Christophe Broca, Charles G. Widmer, Quentin Perrier, Domenico Bosco, Bruno Guerci, Olivier Thaunat, Paolo Malvezzi, Pierre‐Yves Benhamou, Mathieu Armanet, Thierry Berney, Johan Noble, Laurence Kessler, Charles‐Henri Wassmer, Charles Thivolet, Lionel Badet, Igor Tauveron, Laure Esposito, Julia Sabatier, Michel Greget, Pierre Cattan, Luc Frimat, Ekaterine Berishvilli, Ammanuel Morelon
article en
6 citations

Abstract

This study suggests long-term benefits of IT on diabetes-related outcomes. Furthermore, despite the use of immunosuppressive drugs following IT, we observed no significant increase in the risk of cancer. Altogether, these findings highlight a favorable risk-benefit ratio of IT in treating patients with unstable T1D.

Diabetes CareVol. 48(6)
Université Claude Bernard Lyon 1 (FR), Centre National de la Recherche Scientifique (FR), Inserm (FR), Université de Montpellier (FR), Université de Lille (FR), Regenerative NanoMedicine (FR), Centre Hospitalier Universitaire de Besançon (FR), Lille’s Cardiology Hospital (FR), Centre Hospitalier Universitaire de Montpellier (FR), Centre Hospitalier Régional et Universitaire de Nancy (FR), Hospices Civils de Lyon (FR), University Hospital of Geneva (CH), Grenoble Institute of Neurosciences (FR), European Genomic Institute for Diabetes (FR), Geneva College (US), Université Grenoble Alpes (FR)
Agence de la Biomédecine
Good health and well-being
Openalex Percentile: Top 1%
Pancreatic function and diabetes
12.04
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