Haemoconcentration in diagnosing dengue haemorrhagic fever: evidence from a rural Sri Lankan observational study

A 20% increase in haematocrit was not observed during the critical phase, suggesting that haemoconcentration is unreliable for diagnosing DHF in hospitalised patients. This study recommends revisiting the WHO criterion of a 20% haematocrit increase for diagnosing plasma leakage in dengue patients. It suggests that frequent ultrasound scans may be a more reliable method for early detection of plasma leakage.

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Publication Details

Journal
Transactions of the Royal Society of Tropical Medicine and Hygiene
Published
2025-04-02
DOI
https://doi.org/10.1093/trstmh/traf044
Primary Topic
Mosquito-borne diseases and control
Type
article
Field-Weighted Citation Impact
0.00
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article

Haemoconcentration in diagnosing dengue haemorrhagic fever: evidence from a rural Sri Lankan observational study

J. M. R. P. Bandara, Prasanna Weerawansa, Kosala Weerakoon, Chamara Sarathchandra et al.
Transactions of the Royal Society of Tropical Medicine and Hygiene
Mosquito-borne diseases and control
article

Haemoconcentration in diagnosing dengue haemorrhagic fever: evidence from a rural Sri Lankan observational study

J. M. R. P. Bandara, Prasanna Weerawansa, Kosala Weerakoon, Chamara Sarathchandra, Anjana Silva, Sisira Hemananda Siribaddana, Hemal Senanayake
article en

Abstract

A 20% increase in haematocrit was not observed during the critical phase, suggesting that haemoconcentration is unreliable for diagnosing DHF in hospitalised patients. This study recommends revisiting the WHO criterion of a 20% haematocrit increase for diagnosing plasma leakage in dengue patients. It suggests that frequent ultrasound scans may be a more reliable method for early detection of plasma leakage.

Transactions of the Royal Society of Tropical Medicine and HygieneVol. 119(9)
Rajarata University of Sri Lanka (LK)
Good health and well-being
Openalex Percentile: Top 89%
Mosquito-borne diseases and control
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