Evaluation of the Analytical Sensitivity of a Molecular Point-of-Care Assay as Compared to 3 Lateral Flow Assays for Group A Streptococcus
Compared to antigen-based lateral flow assays (LFAs), the molecular ID Now Strep A 2 assay demonstrated a lower LoD, which translates into higher sensitivity. In a clinical setting, this could enable detection of samples with a lower bacterial load that could be missed by low-sensitivity LFAs.
Authors
- Gregory J. Berry (ORCID: https://orcid.org/0000-0002-0767-6826)
- Alamelu Chandrasekaran
- Daniel A. Green (ORCID: https://orcid.org/0000-0002-2394-1319)
- Abdullah Kılıç (ORCID: https://orcid.org/0000-0003-0875-6593)
- Remesh Kumar
- Fann Wu (ORCID: https://orcid.org/0009-0004-4942-7264)
Institutions
- Columbia University Irving Medical Center (US)
- Wake Forest University (US)
Publication Details
- Journal
- The Journal of Applied Laboratory Medicine
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1093/jalm/jfaf042
- Citations
- 3
- Primary Topic
- Streptococcal Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.64
Funders
- Abbott Diagnostics