A Kinetic Chemotaxis Model and Its Diffusion Limit in Slab Geometry

Chemotaxis describes the intricate interplay of cellular motion in response to a chemical signal. In the slab geometry, the motion takes place between two infinite membranes. Like in previous investigations, the asymptotic regime of high tumbling rates is of particular interest. This work provides local existence and uniqueness of solutions to the kinetic equation and shows their convergence towards solutions of a parabolic Keller–Segel model in the asymptotic limit. In addition, convergence rates with respect to the asymptotic parameter are established under additional regularity assumptions on the problem data. Particular difficulties in the analysis are caused by vanishing velocities in the kinetic model as well as the occurrence of boundary terms.

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Publication Details

Journal
Asymptotic Analysis
Published
2025-04-17
DOI
https://doi.org/10.1177/09217134251328514
Primary Topic
Mathematical Biology Tumor Growth
Type
article
Field-Weighted Citation Impact
0.00

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article

A Kinetic Chemotaxis Model and Its Diffusion Limit in Slab Geometry

Kathrin Hellmuth, Nora Philippi, Matthias Schlottbom, Herbert Egger
Asymptotic Analysis
Mathematical Biology Tumor Growth
article

A Kinetic Chemotaxis Model and Its Diffusion Limit in Slab Geometry

Kathrin Hellmuth, Nora Philippi, Matthias Schlottbom, Herbert Egger
article en

Abstract

Chemotaxis describes the intricate interplay of cellular motion in response to a chemical signal. In the slab geometry, the motion takes place between two infinite membranes. Like in previous investigations, the asymptotic regime of high tumbling rates is of particular interest. This work provides local existence and uniqueness of solutions to the kinetic equation and shows their convergence towards solutions of a parabolic Keller–Segel model in the asymptotic limit. In addition, convergence rates with respect to the asymptotic parameter are established under additional regularity assumptions on the problem data. Particular difficulties in the analysis are caused by vanishing velocities in the kinetic model as well as the occurrence of boundary terms.

Asymptotic AnalysisVol. 144(4)
Johannes Kepler University of Linz (AT), University of Würzburg (DE), Johann Radon Institute for Computational and Applied Mathematics (AT), University of Twente (NL)
Deutsche Forschungsgemeinschaft, Studienstiftung des Deutschen Volkes
Openalex Percentile: Top 91%
Mathematical Biology Tumor Growth
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A Kinetic Chemotaxis Model and Its Diffusion Limit in Slab Geometry — Kathrin Hellmuth, Nora Philippi, et al. · Asymptotic Analysis (2025) | TGRS Research Map | TGRS