NATURE CURE

Background: Chronic non-healing ulcers present significant challenges in wound management, particularly with rising antimicrobial resistance. Plant-based compounds offer potential alternatives through their antimicrobial and anti-inflammatory properties. This Case Presentation: randomized controlled trial evaluated a novel plant-based oil formulation containing jasmine (15%), cardamom (20%), licorice (20%), black cumin (25%), and neem (20%) extracts. Sixty patients with chronic non-healing foot ulcers were divided into test (n=30) and control (n=30) groups. The test group received plant-based oil treatment with a burn mesh, while the control group received conventional saline-betadine dressing. The plant-based formulation demonstrated superior outcomes, including significantly greater Discussion: wound size reduction (55% versus 32% at week 4, p<0.001), enhanced granulation tissue formation (85% versus 47% at week 2, p<0.001), lower infection rates (6.7% versus 36.7%, p<0.001), and reduced pain scores (2.8 versus 6.2 on VAS at week 2, p<0.001).The median time for wound closure was notably reduced in the test group, with an average of 28 days compared to 42 days in the control group (p<0.001). Esse Conclusion: ntial oil-based dressings demonstrate efficacy in treating chronic non-healing ulcers, potentially addressing challenges of antimicrobial resistance while improving wound healing parameters and patient comfort.