Forestalling Future Pandemics: Lessons from PISCOV Trial (Ph Based Integrated SARS Cov-2) Immunity in Human Subjects and The Theory of Survival of The Flattest

The world witnessed the havoc done by Covid-19 and is still recuperating from it's aftermath.The only hope, the scientific society can act in order to avert such devastation in future is, from the lessons learned by the Covid-19 pandemic, keeping in view the challenges and opportunities provided by the authors.The Theory of "Survival of the Flattest" hereby proposed by authors, which is a contradiction from the established Theory of "Survival of the Fittest" is verified here as a complementary addendum to Ashby's "Law of Requisite Variety" with the notion that "only the variety can destroy the variety" 1 .The key studies like Digital Organisms Study (2001), Viroid Competition Experiment (2006) and Metabolic Trade-offs and Diversity maintenance (2011) are some major works, which support the "Survival of the Flattest" theory, where genotypes with greater mutational robustness occupy flat curve.We have to look back at the Permian extinction, when life almost ended on earth and death created opportunity for those humble creatures which survived, including one lineage which produced our ancestors, the first mammals.

Publication Details

Published
2025-04-19
DOI
https://doi.org/10.71010/ajcmr.2025-e203
Primary Topic
COVID-19 epidemiological studies
Type
article
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Forestalling Future Pandemics: Lessons from PISCOV Trial (Ph Based Integrated SARS Cov-2) Immunity in Human Subjects and The Theory of Survival of The Flattest

COVID-19 epidemiological studies
article

Forestalling Future Pandemics: Lessons from PISCOV Trial (Ph Based Integrated SARS Cov-2) Immunity in Human Subjects and The Theory of Survival of The Flattest

article en

Abstract

The world witnessed the havoc done by Covid-19 and is still recuperating from it's aftermath.The only hope, the scientific society can act in order to avert such devastation in future is, from the lessons learned by the Covid-19 pandemic, keeping in view the challenges and opportunities provided by the authors.The Theory of "Survival of the Flattest" hereby proposed by authors, which is a contradiction from the established Theory of "Survival of the Fittest" is verified here as a complementary addendum to Ashby's "Law of Requisite Variety" with the notion that "only the variety can destroy the variety" 1 .The key studies like Digital Organisms Study (2001), Viroid Competition Experiment (2006) and Metabolic Trade-offs and Diversity maintenance (2011) are some major works, which support the "Survival of the Flattest" theory, where genotypes with greater mutational robustness occupy flat curve.We have to look back at the Permian extinction, when life almost ended on earth and death created opportunity for those humble creatures which survived, including one lineage which produced our ancestors, the first mammals.

Good health and well-being
COVID-19 epidemiological studies
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Forestalling Future Pandemics: Lessons from PISCOV Trial (Ph Based Integrated SARS Cov-2) Immunity in Human Subjects and The Theory of Survival of The Flattest · (2025) | TGRS Research Map | TGRS