Ginsenoside Rb1 attenuates coronary microvascular inflammatory injury via NDUFS4-SIRT5-DUSP1-mediated mitochondrial quality control in a murine ischemia-reperfusion model
Ginsenoside Rb1 regulates the NDUFS4-SIRT5-DUSP1 axis, modulating the mitochondrial quality control network, inhibiting the inflammatory cascade response, and improved myocardial function.
Authors
- Qiaomin Wu
- Xing Chang (ORCID: https://orcid.org/0000-0002-3788-9881)
- Jinfeng Liu
- Xuanke Guan
- Yanli Wang (ORCID: https://orcid.org/0000-0003-0191-7390)
- Qin Zhang (ORCID: https://orcid.org/0000-0002-9845-4099)
- Ruxiu Liu (ORCID: https://orcid.org/0000-0002-9243-1769)
- Xiangyi Pu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Heriot-Watt University (GB)
- Guang’anmen Hospital (CN)
Publication Details
- Journal
- Journal of Ginseng Research
- Published
- 2025-04-19
- DOI
- https://doi.org/10.1016/j.jgr.2025.04.006
- Citations
- 12
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 9.67