The role of cardiovascular response as a predictor of neurologic disability in children with brain injury – a pilot study
This study suggests that elevated early SBP and HRV indices-particularly LF power measured 12 h after PICU admission-may serve as independent, non-invasive predictors of long-term neurological outcomes in children with severe ABI. These findings support the role of early autonomic activation as a marker of favorable prognosis and underscore the potential value of incorporating cardiovascular and autonomic monitoring into prognostic models and individualized neuroprotective strategies in pediatric neurocritical care.
Authors
- Cristina Granja (ORCID: https://orcid.org/0000-0002-5503-051X)
- Marta João Silva (ORCID: https://orcid.org/0000-0002-5627-7282)
- Cláudia Camila Dias (ORCID: https://orcid.org/0000-0001-9356-3272)
- Inês Azevedo (ORCID: https://orcid.org/0000-0002-0090-8612)
- Hernâni Gonçalves (ORCID: https://orcid.org/0000-0001-6558-8966)
- Ana Isabel Almeida (ORCID: https://orcid.org/0000-0003-0075-5334)
- Maria João Baptista (ORCID: https://orcid.org/0000-0001-9703-882X)
- Rute Almeida (ORCID: https://orcid.org/0000-0001-7755-5002)
- Ana Paula Rocha (ORCID: https://orcid.org/0000-0003-3259-9436)
Institutions
- Universidade do Porto (PT)
- Hospital de São João (PT)
- CUF Porto Hospital (PT)
- Decision Sciences (United States) (US)
- Centre for Health Technology and Services Research (PT)
Publication Details
- Journal
- European Journal of Paediatric Neurology
- Published
- 2025-04-19
- DOI
- https://doi.org/10.1016/j.ejpn.2025.04.009
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundação para a Ciência e a Tecnologia
- Centro de Matemática Universidade do Porto