Peripheral alpha 2-adrenergic antagonist vatinoxan improves the quality of medetomidine–midazolam sedation in Wistar rats
By mitigating the medetomidine-associated effects outside of the central nervous system and reducing the time to loss of consciousness, vatinoxan improved the quality of SC medetomidine-midazolam sedation in laboratory rats.
Authors
- Juhana Honkavaara
- Marja Riitta Raekallio (ORCID: https://orcid.org/0000-0002-2653-003X)
- Piet Finckenberg
- Emily Lindh
- Anna Meller (ORCID: https://orcid.org/0000-0002-9121-210X)
- Karoliina Alm
Institutions
- University of Helsinki (FI)
- Helsinki Institute of Physics (FI)
Publication Details
- Journal
- Veterinary Anaesthesia and Analgesia
- Published
- 2025-04-19
- DOI
- https://doi.org/10.1016/j.vaa.2025.04.002
- Citations
- 3
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 6.57
Funders
- Suomen Eläinlääketieteen Säätiö
- Vetcare