A novel acridine flow cytometry marker to track post‐transfusion amustaline/glutathione pathogen‐reduced red blood cell survival in sickle cell disease patients
Survival of amustaline/glutathione PR-RBCs can be tracked in vivo by flow cytometry for RBC surface acridine with similar sensitivity as biotin, without additional processing or radiolabeling.
Authors
- Anna Erickson (ORCID: https://orcid.org/0000-0003-3937-9217)
- Richard J. Benjamin (ORCID: https://orcid.org/0000-0001-6618-4744)
- Ross M. Fasano (ORCID: https://orcid.org/0000-0001-8692-4041)
- Nina Mufti
- John P. Pitman (ORCID: https://orcid.org/0000-0001-5983-7241)
- John D. Roback (ORCID: https://orcid.org/0000-0001-9952-2252)
- Laurence Corash (ORCID: https://orcid.org/0000-0002-8615-9869)
- Patricia E. Zerra (ORCID: https://orcid.org/0000-0003-3675-2725)
- Marianne E. Yee (ORCID: https://orcid.org/0000-0001-6082-8385)
- Shengnan Huang (ORCID: https://orcid.org/0000-0002-5221-1235)
- Christopher Karim
Institutions
- Grady Memorial Hospital (US)
- Emory University (US)
- Aflac (United States) (US)
- Children's Healthcare of Atlanta (US)
- Cerus (United States) (US)
Publication Details
- Journal
- Transfusion
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1111/trf.18245
- Citations
- 1
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- National Institutes of Health
- Biomedical Advanced Research and Development Authority
- National Heart, Lung, and Blood Institute