Adenoid cystic carcinoma in a male breast: a case report and literature review

Breast adenoid cystic carcinoma (BACC) is a rare occurrence constituting less than 0.1% of primary breast cancers. BACC is even more rare in male patients. Furthermore, there are currently no concrete treatment guidelines for BACC. Therefore, it is imperative to conduct a thoughtful evaluation and diagnostic workup when a potential case is encountered. We report a 63-year old male who initially presented to the dermatologist with a nonhealing inflamed leiomyoma of the left breast, raising suspicion for inflammatory breast cancer. A percutaneous biopsy was performed, and pathology revealed fragments of cribriform and papillary-like carcinoma, leading to a differential diagnosis including adenoid cystic carcinoma and basal-like ductal carcinoma <i>in situ</i>. A modified radical mastectomy was performed, and final surgical pathology revealed BACC. The patient did not receive any adjuvant therapy and is currently without any evidence of disease.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-03-29
DOI
https://doi.org/10.1093/jscr/rjaf226
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
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article

Adenoid cystic carcinoma in a male breast: a case report and literature review

J. W. Odom, Sally Hanna, V K Kapoor, C. R. Anand Moses
Journal of Surgical Case Reports
Salivary Gland Tumors Diagnosis and Treatment
article

Adenoid cystic carcinoma in a male breast: a case report and literature review

J. W. Odom, Sally Hanna, V K Kapoor, C. R. Anand Moses
article en

Abstract

Breast adenoid cystic carcinoma (BACC) is a rare occurrence constituting less than 0.1% of primary breast cancers. BACC is even more rare in male patients. Furthermore, there are currently no concrete treatment guidelines for BACC. Therefore, it is imperative to conduct a thoughtful evaluation and diagnostic workup when a potential case is encountered. We report a 63-year old male who initially presented to the dermatologist with a nonhealing inflamed leiomyoma of the left breast, raising suspicion for inflammatory breast cancer. A percutaneous biopsy was performed, and pathology revealed fragments of cribriform and papillary-like carcinoma, leading to a differential diagnosis including adenoid cystic carcinoma and basal-like ductal carcinoma <i>in situ</i>. A modified radical mastectomy was performed, and final surgical pathology revealed BACC. The patient did not receive any adjuvant therapy and is currently without any evidence of disease.

Journal of Surgical Case ReportsVol. 2025(4)
Augusta University (US), Sisters of Mercy Health System (US), St. Joseph’s Candler Hospital (US)
Good health and well-being
Openalex Percentile: Top 86%
Salivary Gland Tumors Diagnosis and Treatment
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Adenoid cystic carcinoma in a male breast: a case report and literature review — J. W. Odom, Sally Hanna, et al. · Journal of Surgical Case Reports (2025) | TGRS Research Map | TGRS