Complete molar pregnancy: A case report

Introduction: Complete hydatidiform mole, a form of gestational trophoblastic disease, occurs when one sperm fertilizes an empty ovum. Complete trophoblastic proliferation is associated with elevated serum beta human chorionic gonadotropin levels and absence of a fetus. Classic clinical features include abnormal vaginal bleeding, hyperemesis, and enlarged uterus for gestational age. Less common features include hyperthyroidism, early onset pre-eclampsia, and bilateral ovarian thecalutein cysts. Case Report: We present a case of a complete molar pregnancy of a woman who presented to the emergency department at 18 and 4/7 weeks with complaints of irregular vaginal spotting. Serum beta human chorionic gonadotropin level was noted to be 59,401. Transvaginal ultrasound notable for absence of intrauterine gestation with complex heterogeneous material within the uterus. The patient underwent suction dilatation and curettage. Histological examination of curettings confirmed a complete hydatidiform mole. The patient with persistently elevated blood pressures post-operatively necessitated workup for pre-eclampsia, which was negative. Given elevated blood pressures, the patient was started on Labetalol 200 mg twice daily with improvement one month post-procedure. Today, she no longer requires anti-hypertensive medication and beta human chorionic gonadotropin level has appropriately down trended. Conclusion: Our case highlights the need for early imaging to detect abnormalities like hydatidiform moles, which pose significant risks. Early detection improves patient outcomes and ensures proper post-operative care.

Authors

Institutions

Publication Details

Journal
Journal of Case Reports and Images in Obstetrics and Gynecology
Published
2025-04-18
DOI
https://doi.org/10.5348/100201z08rv2025cr
Primary Topic
Gestational Trophoblastic Disease Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Complete molar pregnancy: A case report

Marae Thompson, Sarin A. Soyemi, Ranjitha Vasa, Valini Gosine
Journal of Case Reports and Images in Obstetrics and Gynecology
Gestational Trophoblastic Disease Studies
article

Complete molar pregnancy: A case report

Marae Thompson, Sarin A. Soyemi, Ranjitha Vasa, Valini Gosine
article en

Abstract

Introduction: Complete hydatidiform mole, a form of gestational trophoblastic disease, occurs when one sperm fertilizes an empty ovum. Complete trophoblastic proliferation is associated with elevated serum beta human chorionic gonadotropin levels and absence of a fetus. Classic clinical features include abnormal vaginal bleeding, hyperemesis, and enlarged uterus for gestational age. Less common features include hyperthyroidism, early onset pre-eclampsia, and bilateral ovarian thecalutein cysts. Case Report: We present a case of a complete molar pregnancy of a woman who presented to the emergency department at 18 and 4/7 weeks with complaints of irregular vaginal spotting. Serum beta human chorionic gonadotropin level was noted to be 59,401. Transvaginal ultrasound notable for absence of intrauterine gestation with complex heterogeneous material within the uterus. The patient underwent suction dilatation and curettage. Histological examination of curettings confirmed a complete hydatidiform mole. The patient with persistently elevated blood pressures post-operatively necessitated workup for pre-eclampsia, which was negative. Given elevated blood pressures, the patient was started on Labetalol 200 mg twice daily with improvement one month post-procedure. Today, she no longer requires anti-hypertensive medication and beta human chorionic gonadotropin level has appropriately down trended. Conclusion: Our case highlights the need for early imaging to detect abnormalities like hydatidiform moles, which pose significant risks. Early detection improves patient outcomes and ensures proper post-operative care.

Journal of Case Reports and Images in Obstetrics and GynecologyVol. 11(1)
SUNY Downstate Health Sciences University (US), Washington University in St. Louis (US), Kings County Hospital Center (US)
Openalex Percentile: Top 89%
Gestational Trophoblastic Disease Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Complete molar pregnancy: A case report — Marae Thompson, Sarin A. Soyemi, et al. · Journal of Case Reports and Images in Obstetrics and Gynecology (2025) | TGRS Research Map | TGRS