Liver-Targeting Nanoparticles GA-MSe@AR Treat NAFLD Through Dual Lipid-Lowering and Antioxidant Efficacy
The GA-specific modification enhanced liver-targeted accumulation of the selenium-based nanoparticles, enabling precise targeted delivery of AR. GA-MSe@AR demonstrated superior lipid-lowering efficacy and antioxidant activity in a NAFLD mice model. These findings collectively establish GA-MSe@AR as a promising therapeutic candidate for NAFLD treatment.
Authors
- Min-qiang Lu (ORCID: https://orcid.org/0000-0002-5030-8666)
- Yu Xia
- Qiang Wu (ORCID: https://orcid.org/0000-0003-3922-5189)
- Ning Li (ORCID: https://orcid.org/0000-0003-1208-4638)
- Bin Zhang (ORCID: https://orcid.org/0000-0002-2112-2555)
- Sheng Lei
Institutions
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/ijn.s510577
- Citations
- 5
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 6.77