Autoantibody positivity in chronic hepatitis C pre- and post-direct-acting antiviral therapy: a prospective multicenter south Korean study
ANA positivity was observed in one-third of CHC patients at PreTx, which was significantly higher than that in healthy controls and decreased after SVR. CHC patients with ANA positivity after SVR were older and had more advanced liver disease than those with ANA negativity, suggesting persistent immune dysregulation after cure.
Authors
- Eun Sun Jang (ORCID: https://orcid.org/0000-0003-4274-2582)
- In Hee Kim (ORCID: https://orcid.org/0000-0003-3863-7907)
- Youn Jae Lee (ORCID: https://orcid.org/0000-0003-3854-3388)
- Kyung‐Ah Kim (ORCID: https://orcid.org/0000-0002-6128-6407)
- Woo Jin Chung (ORCID: https://orcid.org/0000-0002-3736-1067)
- Moran Ki (ORCID: https://orcid.org/0000-0002-8892-7104)
- Gwang Hyeon Choi (ORCID: https://orcid.org/0000-0002-8795-8427)
- Dahye Baik (ORCID: https://orcid.org/0000-0002-7112-3740)
- Sung Bum Cho (ORCID: https://orcid.org/0000-0001-9816-3446)
- Sook‐Hyang Jeong (ORCID: https://orcid.org/0000-0002-4916-7990)
- Su Hyun Choi (ORCID: https://orcid.org/0000-0001-7389-1949)
- Young Seok Kim (ORCID: https://orcid.org/0000-0002-7113-3623)
- Byung Seok Lee (ORCID: https://orcid.org/0000-0002-4669-8892)
Institutions
- Soonchunhyang University (KR)
- Seoul National University Bundang Hospital (KR)
- Inje University Ilsan Paik Hospital (KR)
- Inje University Busan Paik Hospital (KR)
- National Cancer Center (KR)
- Chungnam National University Hospital (KR)
- Chonnam National University Hwasun Hospital (KR)
- Bucheon University (KR)
- Jeonbuk National University (KR)
Publication Details
- Journal
- Translational Gastroenterology and Hepatology
- Published
- 2025-04-01
- DOI
- https://doi.org/10.21037/tgh-24-134
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00