Niosomal-Loaded Buccal Films: A Potential System for Oral Mucosal Drug Delivery

The Niosome loaded Buccal drug delivery system includes drug administration through the buccal mucosa, mainly composed of the lining of the cheeks. buccal film Bypass the drug through systemic circulation. But having some issues bioavailability, stability, permeability, rapid drug releases, drug wasteages, waste of time and diminished effect. So, we use nanocarrier, i.e niosomes having less disadvantage compared to other nanocarrier/nanoparticles. Niosomes is carrier, stable and non-toxic form of lipid nanoparticles, Niosome composed of non-ionic surfactant and cholesterol, non-ionic surfactant having no charge, cholesterol help in rigidity of structure and form niosomes. Niosome is prepared by mostly rotatory evaporator and other method also. they resolved the problem in delivery. buccal film is formulated in solvent casting method, Hot-melt extrusion, semisolid casting, rolling, and solid dispersion extrusion. The term "niosomal buccal film" refers to novel technologies and formulations intended to administer medications through the mouth mucosa, avoiding gastrointestinal absorption, enhance bioavailability, improve stability, sustain releases, reducese dose and time consuming. The goal of study is overcome problem related in buccal delivery, buccal delivery has more advantages than other conventional delivery, to know the potential of niosome, and how is more effective, also discussing the future prospective in modern technique, and discuss the differentiation of niosome, liposome.