Pd-Catalyzed Synthesis of Acyclic 1,2-Dioxygenated Dienes and Their Regioselective Decarboxylative Diels–Alder Cycloaddition/Aromatization Reactions to Access Multisubstituted Phenols
A Pd-catalyzed protocol that provides efficient access to acyclic 1,2-dioxygenated dienes has been established. The installation of the bifunctional carbonate electrofuge to the diene cores enabled such dienes to undergo a regioselective decarboxylative Diels-Alder cycloaddition/aromatization reaction, affording diverse synthetic challenging multisubstituted phenols with ease.
Authors
- Yuanfei Zhang (ORCID: https://orcid.org/0000-0003-2667-7055)
- Siyi Qin
- Shuaikang Zhou (ORCID: https://orcid.org/0000-0002-5458-7439)
- Ying Song (ORCID: https://orcid.org/0000-0003-4975-6071)
- Xifang Zhang (ORCID: https://orcid.org/0000-0002-6203-9176)
Institutions
- Chinese Academy of Sciences (CN)
- Fujian Institute of Research on the Structure of Matter (CN)
- Nanning Normal University (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1021/acs.joc.4c02873
- Citations
- 2
- Primary Topic
- Catalytic Alkyne Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Natural Science Foundation of Guangxi Zhuang Autonomous Region
- National Natural Science Foundation of China