Impacts of Zinc, Selenium, and Vitamin E Supplementation on Growth Performance, Hematological and Biochemical Parameters of Blood in Broiler Chickens

Metabolism, lipid synthesis, and reducing oxidative stress contribute to broiler chickens' growth and immunity. The current study examined how zinc, vitamin E, and selenium impact broiler growth, carcass characteristics, hematological and serum biochemical parameters, and profitability. There were 300-day-old straight-run chicks (Indian River) raised in a deep litter system until 28 days old. On day 7, the chicks were randomly divided into four groups of 75 chicks, each group replicated into 3 replications. Supplementation of zinc, selenium, and vitamin E through water was conducted from day 7 to day 28. This experiment was performed during the lifespan of chickens from 0 to 28 days of age. The treatment groups were control (drinking water with no supplementation), Zn (drinking water with 4 ml/L zinc), Se+Vit E (drinking water with 0.25 ml/L E-Sel), and Zn+Se+Vit E (drinking water with both 4 ml/L zinc and 0.25 ml/L E-Sel). The results indicated significant changes in growth and feed conversion ratio among Zn, Se, and Vit-E supplemented groups. Among the supplemented groups, the Zn+Seleium+VitaminE group exhibited higher growth performance, lower cholesterol, and lower production costs. The findings showed no significant changes in dressing characteristics and feed consumption among groups. The combined group of Zn, Se, and Vit-E had a lower abdominal fat content than other supplemented groups. Supplemented with Zn, Se, and Vit-E groups had lower cholesterol and LDL levels than the control group. Serum differential leukocyte count (eosinophils, lymphocytes, neutrophils, and monocytes) and liver and kidney function tests (ALT, AST, creatinine) showed no significant variations between the groups. Antioxidants increased profitability, with the Zn+Se+Vit E group having a higher profit per kg broiler and cost-benefit ratio. Broiler growth performance, dressing characteristics, biochemicals, and hematological indicators are associated with supplementation Zn, Se, and Vit- E. The addition of Zn (4 ml/L) and Se and Vit E solution (E-Sel) (0.25 ml/L) to drinking water could enhance broiler growth performance and reduce cholesterol and high-density lipoprotein (HDL) concentration.