Effect of intravenous alteplase before endovascular therapy for atherothrombotic stroke-related large vessel occlusion: subanalysis of the RESCUE AT-LVO registry
In patients with AT-LVO, IVT before EVT did not improve outcomes and was associated with increased risk of ICH and mortality in those with in situ intracranial occlusion. IVT before EVT may not be recommended in patients with atherosclerotic intracranial occlusions.
Authors
- Hirotoshi Imamura (ORCID: https://orcid.org/0000-0001-8923-7861)
- Hiroto Kakita
- Fumihiro Sakakibara (ORCID: https://orcid.org/0000-0001-5866-6743)
- Hiroyuki Ikeda (ORCID: https://orcid.org/0000-0001-5710-7456)
- Yuji Matsumaru (ORCID: https://orcid.org/0000-0002-4827-8410)
- Kanta Tanaka (ORCID: https://orcid.org/0000-0002-3291-5083)
- Ḱazunori Toyoda (ORCID: https://orcid.org/0000-0002-8346-9845)
- Takanori Sano (ORCID: https://orcid.org/0000-0001-7457-9607)
- Kenichi Todo (ORCID: https://orcid.org/0000-0001-7711-3466)
- Satoshi Namitome (ORCID: https://orcid.org/0009-0001-8321-9109)
- Nobuyuki Sakai (ORCID: https://orcid.org/0000-0002-3289-1210)
- Masafumi Morimoto (ORCID: https://orcid.org/0000-0002-4390-2472)
- Seigo Shindo (ORCID: https://orcid.org/0000-0003-3876-2759)
- Mitsuharu Ueda (ORCID: https://orcid.org/0000-0002-6814-0582)
- Hirotaka Hayashi (ORCID: https://orcid.org/0000-0002-1565-335X)
- Makoto Nakajima (ORCID: https://orcid.org/0000-0003-3547-1307)
- Tatsufumi Nomura
- Mikiya Beppu (ORCID: https://orcid.org/0000-0003-3484-5733)
- Masataka Takeuchi
- Hideyuki Ishihara (ORCID: https://orcid.org/0000-0002-0208-2412)
- Shinichi Yoshimura (ORCID: https://orcid.org/0000-0002-3600-4842)
- Hiroshi Yamagami (ORCID: https://orcid.org/0000-0001-8133-3314)
- Hayato Araki
- Manabu Shirakawa (ORCID: https://orcid.org/0000-0001-5833-2217)
- Yasushi Matsumoto (ORCID: https://orcid.org/0000-0001-8372-356X)
- Kazutaka Uchida (ORCID: https://orcid.org/0000-0003-4780-9598)
- Shinzo Ota (ORCID: https://orcid.org/0000-0002-9490-5577)
- Mikito Hayakawa (ORCID: https://orcid.org/0000-0003-3290-4592)
Institutions
- Hyogo Medical University (JP)
- University of Tsukuba (JP)
- Kumamoto Health Science University (JP)
- Yamaguchi University (JP)
- Tohoku University (JP)
- Prefectural University of Kumamoto (JP)
- Osaka Kaisei Hospital (JP)
- Kurashiki Central Hospital (JP)
- Kindai University Hospital (JP)
- Ohkawara Neurosurgical Hospital (JP)
- Hidaka Hospital (JP)
- Japanese Red Cross Kumamoto Hospital (JP)
- National Cerebral and Cardiovascular Center (JP)
- Kumamoto University Hospital (JP)
- Osaka Hospital (JP)
- Odawara Municipal Hospital (JP)
- Tokyo Women's Medical University (JP)
- Saiseikai Nakatsu Hospital (JP)
- Fuji Heavy Industries Health Insurance Society Ota Memorial Hospital (JP)
- Ise Red Cross Hospital (JP)
- Nishijin Hospital (JP)
- Hyogo University (JP)
- Kumamoto University (JP)
Publication Details
- Journal
- Stroke and Vascular Neurology
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1136/svn-2024-003983
- Citations
- 3
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 4.06