Evaluation of pregabalin-induced oedema using the adverse event spontaneous reporting database and the prescription claims database

This study suggests that oedema and loop diuretic prescriptions are associated with pregabalin use. Pregabalin-induced oedema was more common early in treatment and loop diuretics were more likely to be prescribed when the starting dose of pregabalin was 150 mg/day or more.

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Publication Details

Journal
International Journal of Pharmacy Practice
Published
2025-04-18
DOI
https://doi.org/10.1093/ijpp/riaf012
Primary Topic
Pharmacovigilance and Adverse Drug Reactions
Type
article
Field-Weighted Citation Impact
0.00
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article

Evaluation of pregabalin-induced oedema using the adverse event spontaneous reporting database and the prescription claims database

Miya Oishi, Ryota Tsukioka, Yoshitaka Hasegawa, Mamoru Maeda et al.
International Journal of Pharmacy Practice
Pharmacovigilance and Adverse Drug Reactions
article

Evaluation of pregabalin-induced oedema using the adverse event spontaneous reporting database and the prescription claims database

Miya Oishi, Ryota Tsukioka, Yoshitaka Hasegawa, Mamoru Maeda, Nobuhiro Yasuno, Masao Tsuchiya, Hitoshi Ito
article en

Abstract

This study suggests that oedema and loop diuretic prescriptions are associated with pregabalin use. Pregabalin-induced oedema was more common early in treatment and loop diuretics were more likely to be prescribed when the starting dose of pregabalin was 150 mg/day or more.

International Journal of Pharmacy PracticeVol. 33(3)
Teikyo University Hospital (JP), Shibuya (Japan) (JP)
Openalex Percentile: Top 92%
Pharmacovigilance and Adverse Drug Reactions
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