Urate-lowering effect of delphinidin-3-glucoside in red kidney beans via binding to the FAD site of the XO enzyme
This study identifies Dp-3G, a novel natural agent enriched in red kidney beans, as capable of occupying the FAD site of the XO enzyme, thereby interfering with uric acid synthesis, and suggesting its potential for preventing and treating HUA.
Authors
- Yingtong Jiang
- Minjian Chen (ORCID: https://orcid.org/0000-0002-5742-5080)
- Kun Zhou (ORCID: https://orcid.org/0000-0002-1599-8630)
- Ziyi Li (ORCID: https://orcid.org/0000-0002-5165-8772)
- Yanling Chen (ORCID: https://orcid.org/0000-0002-7287-6488)
- Luo Lu (ORCID: https://orcid.org/0000-0002-1825-4602)
- Mengyuan Zhu (ORCID: https://orcid.org/0000-0003-4825-4168)
- Lei Huang (ORCID: https://orcid.org/0000-0002-9279-878X)
Institutions
- Ministry of Education (KR)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1016/j.jare.2025.04.022
- Citations
- 5
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 6.97