RNA-Sequencing Reveals the Modulation of the NLRP3 Inflammasome by miR-223-3p in Extracellular Vesicles in Bacterial Endophthalmitis
The findings suggest that miR-223-3p could serve as biomarkers in culture-negative cases and therapeutic targets for managing inflammation in bacterial endophthalmitis, potentially guiding treatments aimed at preserving retinal integrity.
Authors
- Dhanwini Rudraprasad (ORCID: https://orcid.org/0000-0001-8059-6251)
- Jayabalan Nirmal (ORCID: https://orcid.org/0000-0001-7864-6053)
- Joveeta Joseph (ORCID: https://orcid.org/0000-0002-8421-1977)
- Dilip Kumar Mishra (ORCID: https://orcid.org/0000-0002-6956-5523)
Institutions
- Manipal Academy of Higher Education (IN)
- L V Prasad Eye Institute (IN)
- Birla Institute of Technology and Science - Hyderabad Campus (IN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1167/iovs.66.4.53
- Citations
- 1
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Hyderabad Eye Research Foundation